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at the National Cancer Institute

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Version: 7.0.0

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U.S. Department of Health and Human Services
National Institutes of Health
National Cancer Institute
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NIH ... Turning Discovery Into Health ®

LDscore Tool

Calculate LD scores and perform LD score regression

Heritability Analysis

Genetic Correlation

LD Score Calculation

Upload pre-munged GWAS sumstats file

Special characters will be removed automatically. Use: A-Z, 0-9, dots, hyphens, and underscores only.

Click here for sample format

Use example data

Population

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Upload pre-munged GWAS sumstats file

Upload pre-munged GWAS sumstats file

Special characters will be removed automatically. Use: A-Z, 0-9, dots, hyphens, and underscores only.

Click here for sample format

Use example data

Population

Select...

Upload *.bed, *.bim, *.fam files

(all three required and must have the same name)

Special characters will be removed automatically. Use: A-Z, 0-9, dots, hyphens, and underscores only.

Click here for sample format

Use example data

Window

Breeze C.E., Yao, X., Park, B., Kanigicherla, M., Lan, Q., Rothman, N., Teschendorff, A.E., Franceschini, N., Berndt, S.I., and Machiela, M.J. (2025). LDscore: a scalable, Python 3-powered web platform for LD score regression analysis. 2025.12.19.695639. bioRxiv https://doi.org/10.64898/2025.12.19.695639